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SELECTIVE INHIBITION OF ERYTHROID CELL DIFFERENTIATION IN THE MOUSE BY LOW DOSES OF ACTINOMYCIN D

โœ Scribed by Kurt R. Reissmann; Kenjiro Ito

Book ID
114878314
Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
294 KB
Volume
149
Category
Article
ISSN
0890-6564

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Delayed inhibition of DNA synthesis in m
Delayed inhibition of DNA synthesis in mouse jejunum by low doses of Actinomycin D
โœ Renato Baserga; Richard D. Estensen; Robert O. Petersen ๐Ÿ“‚ Article ๐Ÿ“… 1966 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 737 KB

Actinomycin D (0.008 pg/gm of body weight) injected intraperitoneally every two hours, produced a prompt 50% inhibition of RNA synthesis in the jejunum of mice, and a delayed inhibition of DNA synthesis, that reached its maximum inhibition (68% of control values) 4.5 hours after the first injection