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Selective enrichment of sialic acid–containing glycopeptides using titanium dioxide chromatography with analysis by HILIC and mass spectrometry

✍ Scribed by Palmisano, Giuseppe; Lendal, Sara Eun; Engholm-Keller, Kasper; Leth-Larsen, Rikke; Parker, Benjamin L; Larsen, Martin R

Book ID
109946831
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
499 KB
Volume
5
Category
Article
ISSN
1750-2799

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## Abstract Comprehensive glycoprotein characterization based on mass spectrometry (MS) is challenging because of low concentration of glycopeptides and suppression effect of abundant non‐glycosylated peptides in MS. Therefore, it is vital to enrich glycopeptides before MS analysis. A new method wa