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Selective drug transport and P-glycoprotein activity in an in vitro blood-brain barrier model

✍ Scribed by B. Joly; O. Fardel; R. Cecchelli; C. Chesné; C. Puozzo; A. Guillouzo

Book ID
116153010
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
661 KB
Volume
9
Category
Article
ISSN
0887-2333

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The influence of plasma zinc concentration on the rate of zinc transport into the brain was examined using an in vitro model of the blood-brain barrier. The model was constructed by culturing porcine brain capillary endothelial cells on porous membrane filters suspended between two chambers of fluid