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Selective cleavage of tert-butyldimethylsilyl ethers with neutral alumina

✍ Scribed by Feixas, Joan; Capdevila, Anna; Camps, Francisco; Guerrero, Angel


Book ID
120243077
Publisher
The Royal Society of Chemistry
Year
1992
Tongue
English
Weight
235 KB
Volume
19
Category
Article
ISSN
0022-4936

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Cleavage of tert-butyldimethylsilyl ethe
✍ Jaume FarrΓ s; Carme Serra; Jaume Vilarrasa πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 181 KB

A general method for the selective cleavage of tert-butyldimethylsilyl ethers in the presence of tert-butyldiphenylsilyl ones has been established using a combination of H20 and a concentrated solution of LiCI in DMF at 90 Β°C. Since no acids, bases, reducing or oxidizing agents are used, the method