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Selective Attachment of Oligonucleotides to Interleukin-1β and Targeted Delivery to Cells

✍ Scribed by Chollet, André

Book ID
118022382
Publisher
Taylor and Francis Group
Year
1990
Tongue
English
Weight
422 KB
Volume
9
Category
Article
ISSN
0732-8311

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## Abstract Interleukin‐1 induces release of NO and PGE~2~ and production of matrix degrading enzymes in chondrocytes. In osteoarthritis (OA), IL‐1 continually, or episodically, acts on chondrocytes in a paracrine and autocrine manner. Human chondrocytes in chondron pellet culture were treated chro