Bacterial selectivity and plausible mode
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Ka Hyon Park; Yoonkyung Park; II-Seon Park; Kyung-Soo Hahm; Song Yub Shin
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Article
📅
2008
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John Wiley and Sons
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English
⚖ 220 KB
## Abstract To develop novel Pro‐rich model AMPs with shorter length and higher bacterial selectivity/therapeutic index (TI) than natural AMP, indolicidin, we synthesized a series of undodecapeptides derived from the sequence XXPXXPWXPXX‐NH~2~ (X indicates Leu or Lys) with different ratios of Lys a