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Selective Acylation of Primary Amines in Peptides and Proteins

✍ Scribed by Abello, Nicolas; Kerstjens, Huib A. M.; Postma, Dirkje S.; Bischoff, Rainer


Book ID
121337712
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
177 KB
Volume
6
Category
Article
ISSN
1535-3893

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Selective benzoylation of primary amines
✍ Tao Wang; Zhongxing Zhang; Nicholas A. Meanwell πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 120 KB

Compounds containing both primary and secondary amine moieties in the same molecule were treated sequentially with two equivalents of n-butyllithium at room temperature, two equivalents of TMSCI, one equivalent of nbutyllithium and one equivalent of benzoyl chloride, to afford mono-benzoylated diami