✦ LIBER ✦

Segmental bone regeneration using a load-bearing biodegradable carrier of bone morphogenetic protein-2

✍ Scribed by Tien-Min G. Chu; Stuart J. Warden; Charles H. Turner; Rena L. Stewart

Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 570 KB
Volume: 28
Category: Article
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2006.09.004

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Restoration of segmental bone defects in

Restoration of segmental bone defects in rabbit radius by biodegradable capsules containing recombinant human bone morphogenetic protein-2

✍ Mori, Masahiro ;Isobe, Masatsugu ;Yamazaki, Yasuharu ;Ishihara, Kazuhiko ;Nakaba 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 517 KB

Recombinant human bone morphogenetic protein-2 (rhBMP-2) was encapsulated in biodegradable poly(DL-lactide-co-glycolide) (PLGA) capsules to regenerate bone by controlling the release rate of rhBMP-2. The rhBMP-2/PLGA capsules containing 12 g of rhBMP-2 were implanted in seven 15-mm segmental defects

Ectopic induction of cartilage and bone

Ectopic induction of cartilage and bone by bovine bone morphogenetic protein using a biodegradable polymeric reservoir

✍ Yamazaki, Yasuharu ;Oida, Shin-ichiro ;Ishihara, Kazuhiko ;Nakabayashi, Nobuo 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 471 KB

Two kinds of bone morphogenetic protein (BMP) containing polymeric reservoirs made from poly(1actide-coglycolide) (PLG) and a mixture of PLGipoly(ethy1ene glycol) (PEG) (PLGPEG) were implanted into mice femoral muscles. In the PLGiPEG reservoir with BMP, bone formation was induced within 3 weeks. On

Experimental studies on bone induction u

Experimental studies on bone induction using low-molecular-weight poly (DL-lactide-co-glycolide) as a carrier for recombinant human bone morphogenetic protein-2

✍ Bessho, K. ;Carnes, D. L. ;Cavin, R. ;Ong, J. L. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 398 KB

## Abstract An appropriate carrier acting as a slow delivery vehicle for the BMPs is required for maximal clinical effectiveness of these bone‐inductive proteins. The purpose of this study was to evaluate a low‐molecular‐weight PLGA copolymer as a synthetic, biodegradable carrier for rhBMP‐2 implan

Bone regeneration using a naturally grow

Bone regeneration using a naturally grown HA/TCP carrier loaded with rh BMP-2 is independent of barrier-membrane effects

✍ C. Schopper; D. Moser; E. Spassova; W. Goriwoda; G. Lagogiannis; B. Hoering; R. 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 585 KB

## Abstract The present study investigated whether bone regeneration and biomaterial replacement would be improved by loading of biogenous biphasic biomaterial scaffolds (HA/TCP ratio 30/70) with rhBMP‐2, and whether the placement of three barrier membranes differing in structure and porosity (prot

Carrier dependent cell differentiation o

Carrier dependent cell differentiation of bone morphogenetic protein-2 induced osteogenesis and chondrogenesis during the early implantation stage in rats

✍ Takita, H. ;Vehof, J. W. M. ;Jansen, J. A. ;Yamamoto, M. ;Tabata, Y. ;Tamura, M. 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 403 KB

## Abstract To evaluate the osteoinductive effects of recombinant human bone morphogenetic protein (rhBMP)‐2 during the early stages of rat ectopic bone formation, we prepared two distinct carriers. Two carriers, insoluble bone matrix (IBM) and fibrous glass membrane (FGM) were combined with rhBMP‐

Repair of long intercalated rib defects

Repair of long intercalated rib defects in dogs using recombinant human bone morphogenetic protein-2 delivered by a synthetic polymer and beta-tricalcium phosphate

✍ Masatoshi Hoshino; Takeshi Egi; Hidetomi Terai; Takashi Namikawa; Minori Kato; Y 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 400 KB 👁 1 views

## Abstract Long intercalated defects in canine ribs can be repaired successfully using porous beta‐tricalcium phosphate (β‐TCP) cylinders, infused with a biodegradable polymer (poly D,L‐lactic acid‐polyethylene block copolymer) containing recombinant human bone morphogenetic protein‐2 (rhBMP‐2). W