𝔖 Bobbio Scriptorium
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Secretory phospholipase A2inhibitors and calmodulin antagonists as inhibitors of cytosolic phospholipase A2

✍ Scribed by William C. Hope; Ting Chen; Douglas W. Morgan


Publisher
SP Birkhäuser Verlag Basel
Year
1993
Tongue
English
Weight
204 KB
Volume
39
Category
Article
ISSN
1420-908X

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The use of conformationally restricted phospholipids 1 and 2 has been employed to understand the conformational preference of phospholipase A2 (PLA2) for substrate phospholipids. Inhibition of porcine pancreatic PLA2 with 1 and 2 indicated a two-to fivefold preference for the distal isomer 2 over th