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Secretion of endogenous kallikreins 2 and 3 by androgen receptor-transfected PC-3 prostate cancer cells

✍ Scribed by Alexandra Kollara; Eleftherios P. Diamandis; Theodore J. Brown


Book ID
117668511
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
362 KB
Volume
84
Category
Article
ISSN
0960-0760

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Androgen receptors are expressed at a low level in the cell line PC-3, which does not respond to either androgens or antiandrogens. If these cells are exposed to natural beta-interferon (beta-IFN) a reduction in cell growth and an increase in androgen receptors, evaluated by both biochemical and imm