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Secondary Metabolites from the Leaves of Litsea lii var. nunkao-tahangensis

✍ Scribed by Tzu-Ann Wang; Ming-Jen Cheng; Shiow-Ju Lee; Cheng-Wei Yang; Hsun-Shuo Chang; Ih-Sheng Chen


Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
209 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

Investigation of the leaves extract of Litsea lii var. nunkao‐tahangensis led to the isolation of five new butanolides, litsealiicolide A (1), isolitsealiicolide A (2), litsealiicolide B (3), isolitsealiicolide B (4), and isolitsealiicolide C (5), along with 17 known compounds. Their structures were determined through in‐depth spectroscopic and mass‐spectrometric analyses. Among the isolates, compounds 1 and 2 were cytotoxic against MCF‐7, NCI‐H460, and SF‐268 cell lines in vitro. Compound 5 and isolinderanolide B (6) showed marginal cytotoxic activity against these three cell lines in vitro.


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