Secondary Metabolites from the Leaves of Litsea lii var. nunkao-tahangensis
✍ Scribed by Tzu-Ann Wang; Ming-Jen Cheng; Shiow-Ju Lee; Cheng-Wei Yang; Hsun-Shuo Chang; Ih-Sheng Chen
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- German
- Weight
- 209 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0018-019X
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✦ Synopsis
Abstract
Investigation of the leaves extract of Litsea lii var. nunkao‐tahangensis led to the isolation of five new butanolides, litsealiicolide A (1), isolitsealiicolide A (2), litsealiicolide B (3), isolitsealiicolide B (4), and isolitsealiicolide C (5), along with 17 known compounds. Their structures were determined through in‐depth spectroscopic and mass‐spectrometric analyses. Among the isolates, compounds 1 and 2 were cytotoxic against MCF‐7, NCI‐H460, and SF‐268 cell lines in vitro. Compound 5 and isolinderanolide B (6) showed marginal cytotoxic activity against these three cell lines in vitro.
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