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Search for small molecule activators of latent HIV

✍ Scribed by Geleziunas, Romas; Stepan, George; Wei, George; Yu, Helen; Graupe, Michael; Pagratis, Nikos; Barnes, Tiffany; Cihlar, Tomas; Hesselgesser, Joe

Book ID
115022226
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
72 KB
Volume
9
Category
Article
ISSN
1742-4690

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## Abstract Activation of the p53 tumour suppressor is predicted to have therapeutically beneficial effects. Many current anti‐cancer therapies activate the p53 response __via__ DNA damage. Non‐genotoxic activation of the p53 pathway would open the way to long‐term and possibly prophylactic treatme