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Screening of 17 Guatemalan medicinal plants for platelet antiaggregant activity

✍ Scribed by Rosa Villar; José María Calleja; Claudia Morales; Armando Cáceres

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
114 KB
Volume
11
Category
Article
ISSN
0951-418X

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✦ Synopsis

The platelet antiaggregant activity of 17 aqueous extracts of plants traditionally used in Guatemala for the treatment of 'blood disorders' and parasitic infections were assayed. The aggregation of washed human platelets induced by thrombin (0.075 U/mL) was inhibited by extracts of Tridax procumbens, Tagetes lucida, Annona reticulata, Neurolaena lobata, Bixa orellana, Rauvolfia tetraphylla, Petiveria alliacea and Tecoma stans. The other extracts did not have clear inhibitory effects, and indeed caused some platelet aggregation themselves, in the absence of thrombin.

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