Preliminary screening of some traditional Zulu medicinal plants for antineoplastic activities versus the HepG2 cell line
✍ Scribed by A. R. Opoku; M. Geheeb-Keller; J. Lin; S. E. Terblanche; A. Hutchings; A. Chuturgoon; D. Pillay
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 60 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0951-418X
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✦ Synopsis
to the Vitaceae family, were evaluated to determine their therapeutic potentials as antineoplastic agents. The antiproliferative activity in vitro against HepG2 cells was determined. Twenty-two of the twenty-seven crude plant extracts showed activities ranging from 25% to 97% inhibition of proliferation when compared with the control which showed no inhibitory activity. Higher degrees of growth inhibition were found in aqueous root extracts in comparison with the methanol extracts of the same plant parts. The results show potential antineoplastic activity, indicating some scientific validation for traditional usage.