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Screening for mutations of the IRP2 gene in Parkinson’s disease patients with hyperechogenicity of the substantia nigra

✍ Scribed by J. Deplazes; K. Schöbel; H. Hochstrasser; P. Bauer; U. Walter; S. Behnke; J. Spiegel; G. Becker; O. Riess; D. Berg

Publisher
Springer
Year
2004
Tongue
English
Weight
116 KB
Volume
111
Category
Article
ISSN
1435-1463

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## Abstract Using transcranial sonography, an area of hyperechogenicity at the substantia nigra (SN) may be detected as a typical marker in patients with Parkinson's disease (PD) as well as in approximately 9% of healthy subjects vulnerable to nigrostriatal impairment. In this longitudinal study, w