𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Five-year follow-up study of hyperechogenicity of the substantia nigra in Parkinson's disease

✍ Scribed by Daniela Berg; Berthold Merz; Karlheinz Reiners; Markus Naumann; Georg Becker

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
143 KB
Volume
20
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Using transcranial sonography, an area of hyperechogenicity at the substantia nigra (SN) may be detected as a typical marker in patients with Parkinson's disease (PD) as well as in approximately 9% of healthy subjects vulnerable to nigrostriatal impairment. In this longitudinal study, we provide evidence that the area of SN hyperechogenicity does not change in the course of PD. In conjunction with earlier findings in children and adolescents, this evidence indicates that, from late adolescence onward, this ultrasound finding is a trait marker for nigrostriatal vulnerability. Β© 2004 Movement Disorder Society

πŸ“œ SIMILAR VOLUMES

Transcranial imaging of substantia nigra
Transcranial imaging of substantia nigra hyperechogenicity in a Taiwanese cohort of Parkinson's disease
✍ Yu-Wen Huang; Jiann-Shing Jeng; Chung-Fen Tsai; Li-Ling Chen; Ruey-Meei Wu πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 117 KB πŸ‘ 1 views

## Abstract Transcranial Doppler imaging (TCDI) has been used as a noninvasive diagnostic tool to differentiate Parkinson's disease (PD) from atypical parkinsonism by detecting hyperechogenicity in the substantia nigra (SN). To our knowledge, no TCDI data are available for Asian populations, and TC

Substantia nigra hyperechogenicity as a
Substantia nigra hyperechogenicity as a marker of predisposition and slower progression in Parkinson's disease
✍ Katherine J. Schweitzer; RΓΌdiger Hilker; Uwe Walter; Lothar Burghaus; Daniela Be πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 117 KB

## Abstract Increased echogenic size (hyperechogenicity) of the substantia nigra (SN) is a characteristic transcranial sonography finding in patients with Parkinson's disease (PD). The SN echogenic size does not change in the course of the disease. In order to see whether this stable ultrasound mar

High resolution magnetic susceptibility
High resolution magnetic susceptibility mapping of the substantia nigra in Parkinson's disease
✍ Ashley K. Lotfipour; Samuel Wharton; Stefan T. Schwarz; V. Gontu; Andreas SchΓ€fe πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 426 KB πŸ‘ 1 views

## Abstract ## Purpose: To determine if tissue magnetic susceptibility is a more direct marker of tissue iron content than other MR markers of iron. This study presents the first quantitative, in vivo measurements of the susceptibility of the substantia nigra in patients with Parkinson's disease.

Two-year follow-up of subthalamic deep b
Two-year follow-up of subthalamic deep brain stimulation in Parkinson's disease
✍ Jan Herzog; Jens Volkmann; Paul Krack; Florian Kopper; Monika PΓΆtter; Delia Lore πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 74 KB πŸ‘ 1 views

## Abstract We studied 48 patients after bilateral subthalamic nucleus deep brain stimulation (STN‐DBS) who were evaluated 6 months after the surgical procedure using the Unified Parkinson's Disease Rating Scale (UPDRS) in a standardized levodopa test. Additional follow‐up was available in 32 patie

Raman microspectroscopy of the brain tis
Raman microspectroscopy of the brain tissues in the substantia nigra and MPTP-induced Parkinson's disease
✍ C. W. Ong; Z. X. Shen; Y. He; T. Lee; S. H. Tang πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 125 KB πŸ‘ 2 views

The substantia nigra of the rostral mid-brain of a monkey was studied using Raman microspectroscopy. The white and grey matter could be clearly distinguished and their relative proportions evaluated from the Raman peaks in the 3000 cm-1 region. Raman spectra obtained from the substantia nigra for bo