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Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas

✍ Scribed by Lucia Rosaria De Vitis,Andrea Tedde,Francesca Vitelli,Franco Ammannati…


Book ID
118292004
Publisher
Springer
Year
1996
Tongue
English
Weight
64 KB
Volume
97
Category
Article
ISSN
0340-6717

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## Abstract The role of the __NF2__ gene in the development of meningiomas has recently been documented; inactivating mutations plus allelic loss at 22q, the site of this gene (at 22q12), have been identified in both sporadic and neurofibromatosis type 2–associated tumors. Although epigenetic inact