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Screening and determination of β-blockers, narcotic analgesics and stimulants in urine by high-performance liquid chromatography with column switching

✍ Scribed by M.T. Saarinen; H. Sirén; M.-L. Riekkola

Publisher: Elsevier Science
Year: 1995
Weight: 380 KB
Volume: 664
Category: Article
ISSN: 0378-4347
DOI: 10.1016/0378-4347(94)00497-s

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## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The clean‐up and separation of the samp