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Automated determination of hypoxanthine and xanthine in urine by high-performance liquid chromatography with column switching

✍ Scribed by Satoshi Sumi; Kiyoshi Kidouchi; Satoru Ohba; Yoshiro Wada


Publisher
Elsevier Science
Year
1995
Weight
208 KB
Volume
670
Category
Article
ISSN
0378-4347

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## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The clean‐up and separation of the samp