Two doses of sclerostin antibody in cyno
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Michael S Ominsky; Fay Vlasseros; Jacquelin Jolette; Susan Y Smith; Brian Stouch
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Article
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2010
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American Society for Bone and Mineral Research
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English
⚖ 691 KB
## Abstract The development of bone‐rebuilding anabolic agents for treating bone‐related conditions has been a long‐standing goal. Genetic studies in humans and mice have shown that the secreted protein sclerostin is a key negative regulator of bone formation. More recently, administration of scler