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Salvianolic acid B modulates the expression of drug-metabolizing enzymes in HepG2 cells

✍ Scribed by Qing-Lan Wang; Quoc Wu; Yan-Yan Tao; Cheng-Hai Liu; Hani El-Nezami

Book ID
117792671
Publisher
Zhejiang University School of Medicine, China
Year
2011
Tongue
English
Weight
582 KB
Volume
10
Category
Article
ISSN
1499-3872

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## Abstract Primary cultures of human hepatocytes and hepatoma cell line HepG2 are frequently used to evaluate the hepatic disposition of drugs and other xenobiotics. To check the variability of the expression of drug‐metabolizing enzymes in these in vitro models, expression of genes coding for sev