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Expression and activities of several drug-metabolizing enzymes in LLC-PK1 cells

✍ Scribed by Raymond J. Gonzalez; Joan B. Tarloff

Book ID
116919206
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
443 KB
Volume
18
Category
Article
ISSN
0887-2333

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In LLC-PK, porcine epithelial cells, the urokinase-type plasminogen activator (u-PA) mRNA and protein can be induced either by stimulation of the protein kinase C (PKC) pathway using a tumor promoter (PMA) or by stimulation of the protein kinase A (PKA) pathway with calcitonin SCT). By PKC, to LLC-P