Salivary Epstein-Barr virus DNA level in patients with nasopharyngeal carcinoma following radiotherapy
β Scribed by Edmond H.N. Pow; Mike Y.T. Law; Peter C.S. Tsang; Ranawaka A.P.M. Perera; Dora L.W. Kwong
- Book ID
- 113834048
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 159 KB
- Volume
- 47
- Category
- Article
- ISSN
- 1368-8375
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## RESULTS. In specimens from 107 patients with NPC, EBV was detected by PCR in 2 Department of Pathology, the Johns Hopkins 97 cases (90.7%) and by EBER in situ hybridization in 105 cases (98.1%). In speci-
A salt-dependent DNA polymerase activity was demonstrated in the culture of an EBV-producing, lymphoblastoid cell line (NPC-204 cells) treated with 5-iodo-2'-deoxyuridine (IUdR). There was a high frequency of levels of antibody to this enzyme in sera of patients with nasopharyngeal carcinoma (NPC).