This review deals with the safety and antidepressant efficacy of selective serotonin re-uptake inhibitors (SSRIs). At present, five SSRIs are used therapeutically in European countries (fluvoxamine, fluoxetine, paroxetine, sertraline and citalopram). The antidepressant efficacy of these drugs has be
Safety and efficacy of bupropion, a novel antidepressant
β Scribed by Robert L. Dufresne; Dr. Robert E. Becker; Robert Bltzer; Richard L. Wagner; Harbans Lal
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 454 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0272-4391
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Bupropion hydrochloride 1 (2-tert-butylamino-3'-chloropropiophenone hydrochloride) was synthesized in the [l\*C]-labelled form with specific activity 36.5 mCi/mmol suitable for drug metabolism, distribution and pharmacokinetic studies. The drug was synthesized in the [3H]-labelled form with specifi
Efficacy and safety of novel antipsychotic (AP) drugs (amisulpride, olanzapine, quetiapine, ziprasidone and zotepine) have been reviewed. Data on their antipsychotic efficacy and side effects profile have been evaluated only on the basis of controlled trials so far published. Overall, all these drug
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