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Sa.22. IRF5 Risk Haplotype is Associated with High Serum Interferon Alpha Activity in Systemic Lupus Erythematosus Patients

✍ Scribed by Timothy Niewold; Jennifer Kelly; John Harley; Mary Crow

Book ID: 113540385
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 54 KB
Volume: 127
Category: Article
ISSN: 1090-2341
DOI: 10.1016/j.clim.2008.03.243

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## Abstract ## Objective To determine whether specific isoforms of IRF5 are transcribed in patients with systemic lupus erythematosus (SLE) who have risk genotypes in the exon 1B donor splice site at single‐nucleotide polymorphism (SNP) no. rs2004640. ## Methods Peripheral blood mononuclear cell

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