𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

✍ Scribed by Timothy B. Niewold; Jennifer A. Kelly; Marie H. Flesch; Luis R. Espinoza; John B. Harley; Mary K. Crow


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
485 KB
Volume
58
Category
Article
ISSN
0004-3591

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Structural insertion/deletion variation
✍ Sergey V. Kozyrev; Susanna Lewén; Prasad M. V. Linga Reddy; Bernardo Pons-Estel; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 234 KB 👁 1 views

## Abstract ## Objective To determine whether specific isoforms of IRF5 are transcribed in patients with systemic lupus erythematosus (SLE) who have risk genotypes in the exon 1B donor splice site at single‐nucleotide polymorphism (SNP) no. rs2004640. ## Methods Peripheral blood mononuclear cell

Network analysis of associations between
✍ Corinna E. Weckerle; Beverly S. Franek; Jennifer A. Kelly; Marissa Kumabe; Rache 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

## Abstract ## Objective Interferon‐α (IFNα) is a primary pathogenic factor in systemic lupus erythematosus (SLE), and high IFNα levels may be associated with particular clinical manifestations. The prevalence of individual clinical and serologic features differs significantly by ancestry. This st

Activation of the interferon-α pathway i
✍ Kyriakos A. Kirou; Christina Lee; Sandhya George; Kyriakos Louca; Margaret G. E. 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 170 KB

## Abstract ## Objective Gene‐expression studies have demonstrated increased expression of interferon (IFN)–inducible genes (IFIGs) in peripheral blood mononuclear cells (PBMCs) of many patients with systemic lupus erythematosus (SLE), with a predominant effect of type I IFN. This study examined t