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Sa1773 Clinicopathological and Molecular Correlates of PIK3CA Mutations in Gastric Cancer

✍ Scribed by Sukawa, Yasutaka; Yamamoto, Hiroyuki; Nosho, Katsuhiko; Adachi, Yasushi; Kunimoto, Hiroaki; Igarashi, Hisayoshi; Nakazawa, Mayumi; Suzuki, Hiromu; Sasaki, Shigeru; Shinomura, Yasuhisa

Book ID
122246089
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
56 KB
Volume
142
Category
Article
ISSN
0016-5085

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## Abstract Mutation of __PIK3CA__, the gene coding for the p110Ξ± catalytic subunit of phosphoinositide 3‐kinase (PI3K), has been reported in a limited range of human tumors. We now report that __PIK3CA__ is also mutated in esophageal tumors. Single‐strand conformational polymorphism (SSCP) and den