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S1P receptor signalling and RGS proteins; expression and function in vascular smooth muscle cells and transfected CHO cells

✍ Scribed by Mariëlle C. Hendriks-Balk; Pieter B. van Loenen; Najat Hajji; Martin C. Michel; Stephan L.M. Peters; Astrid E. Alewijnse

Book ID
113587897
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
602 KB
Volume
600
Category
Article
ISSN
0014-2999

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## Abstract Sphingosine‐1‐phosphate (S1P), acting through five closely related G‐protein coupled receptors termed S1P~1–5~, has recently emerged as a possible regulator of smooth muscle cell (SMC) physiology with the potential to induce contraction, proliferation and stress fiber formation. In the