𝔖 Bobbio Scriptorium
✦   LIBER   ✦

(S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: a putative 5-HT1A-receptor antagonist

✍ Scribed by Hillver, Sven Erik; Bjoerk, Lena; Li, Yi Lin; Svensson, Bjoern; Ross, Svante; Anden, Nils Erik; Hacksell, Uli

Book ID
127357821
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
553 KB
Volume
33
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

ChemInform Abstract: (-)-5-Methyl-8-hydr
ChemInform Abstract: (-)-5-Methyl-8-hydroxy-(di-n-propylamino)tetralin: A New 5-HT1A Receptor Antagonist.
✍ A.-C. TRILLAT; M. MATHE-ALLAINMAT; B. BREMONT; I. MALAGIE; C. JACQUOT; A. M. GAR 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 34 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

Synthesis of R-(+)- and S-(−)-8-hydroxy-
Synthesis of R-(+)- and S-(−)-8-hydroxy-2-(N, N-dipropylamino)-[2-3H] tetralin. HCl (8-OH-DPAT) a 5HT1A receptor agonist
✍ M. J. Ackland; L. G. Dring; J. R. Jones; N. Gilon 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 364 KB

## Abstract The title compounds were synthesised in 7 steps from 1,7‐dihydroxynaphthalene as follows: 1,7‐dihydroxynaphthalene was methylated and subjected to a Birch reduction to yield 8‐methoxy‐2‐tetralone. Reductive amination with sodium cyanoboro[^3^H]hydride and n‐propylamine gave 8‐methoxy‐2‐