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Ruthenium(IV)-Catalyzed Markovnikov Addition of Carboxylic Acids to Terminal Alkynes in Aqueous Medium

✍ Scribed by Cadierno, Victorio; Francos, Javier; Gimeno, José


Book ID
127261736
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
981 KB
Volume
30
Category
Article
ISSN
0276-7333

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Ruthenium-catalyzed selective anti-Marko
✍ Karen Melis; Pawel Samulkiewicz; Jacek Rynkowski; Francis Verpoort 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 142 KB

Carboxylic acids react with terminal alkynes in the presence of a catalytic amount of RuCl x (p-cymene)(triazol-5-ylidene) to selective generate Z-alk-1-en-1-yl esters. The anti-Markovnikov and trans addition on the terminal alkyne gives access to Z-alkene derivatives of phenylacetylene, t-butylacet