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General Synthesis of (Z)-Alk-1-en-1-yl Esters via Ruthenium-Catalyzed anti-Markovnikov trans-Addition of Carboxylic Acids to Terminal Alkynes

✍ Scribed by Doucet, Henri; Martin-Vaca, Blanca; Bruneau, Christian; Dixneuf, Pierre H.


Book ID
126193296
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
992 KB
Volume
60
Category
Article
ISSN
0022-3263

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Ruthenium-catalyzed selective anti-Marko
✍ Karen Melis; Pawel Samulkiewicz; Jacek Rynkowski; Francis Verpoort 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 142 KB

Carboxylic acids react with terminal alkynes in the presence of a catalytic amount of RuCl x (p-cymene)(triazol-5-ylidene) to selective generate Z-alk-1-en-1-yl esters. The anti-Markovnikov and trans addition on the terminal alkyne gives access to Z-alkene derivatives of phenylacetylene, t-butylacet