𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Rotating frame spin-lattice relaxation experiments and the problem of intramolecular motions of peptides in solution

✍ Scribed by Hermann E. Bleich; Jay A. Glasel

Publisher
Wiley (John Wiley & Sons)
Year
1978
Tongue
English
Weight
719 KB
Volume
17
Category
Article
ISSN
0006-3525

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The application of rotating frame spin‐lattice relaxtion to the determination of the intramolecular motions in peptides is discussed, and results are presented on the application of ^13^C T~1__p__~ to peptide microdynamics in solution. The effective molecular rotational reorientation times at the amide and amino nitrogens may be derived from appropriate data on__T__~1__p__~ of the carbons adjacent to them. We also show by theoretical caculations that ^1^H and ^13^C T~1__p__~ experiments of suitable ^2^H and ^15^N substituted peptides will allow intramolecular main‐ and sidechain motions, characterized by times in the range 10^−1^–10^−6^ sec, to be investigated.

📜 SIMILAR VOLUMES

Rotating Frame Analog of Spin-Locking an
Rotating Frame Analog of Spin-Locking and Spin–Lattice Relaxation in the Doubly Rotating Frame
✍ Noriyuki Tabuchi; Hiroshi Hatanaka 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 79 KB

The present paper reports the achievement of the rotating-frame analog of spin-locking and its application to the precise measurements of the spin-lattice relaxation time T(1DR) in the doubly rotating frame. After the magnetization is aligned along the resonant RF field H(1), a pulse sequence of a l

Assesment of protein reorientational dif
Assesment of protein reorientational diffusion in solution by 13C off-resonance rotating frame spin–lattice relaxation: Effect of polydispersity
✍ Courtney F. Morgan; Thomas Schiliech; G. Herbert Caines 📂 Article 📅 1990 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 482 KB

The '"C off-resonance rotating frame spin-lattice relaxation technique is applicable to the study of protein rotational diffusion behavior in both model in vitro and in vivo systems. The original formalism of James and co-workers [(1978) J. Am. Chem. SOC. 100, 3590-35941 was constrained by the assum

Rotating frame spin lattice relaxation i
Rotating frame spin lattice relaxation in a swine model of chronic, left ventricular myocardial infarction
✍ Walter R. T. Witschey; James J. Pilla; Giovanni Ferrari; Kevin Koomalsingh; Moha 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 329 KB

## Abstract T1ρ relaxation times were quantified in a swine model of chronic, left ventricular myocardial infarction. It was found that there were low frequency relaxation mechanisms that suppress endogenous contrast at low spin‐lock amplitudes and in T2‐weighted images. A moderate amplitude spin‐l

Assessment of protien reorientational di
Assessment of protien reorientational diffusion in solution by 13C off-resonance rotating frame spin–lattice relaxation: Effect of anisotropic tumbling
✍ Courtesy F. Morgan; Thomas Schlieich; G. Herbert Caines; David Michael 📂 Article 📅 1990 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 811 KB

## Abstract The ^13^C off‐resonance rotating frame spin‐lattice relaxation technique is applicable to the study of protien rotational diffusion behaviour in a variety of experimental situations. The original formalism of James and co‐workers (1978) (__J. Amer. Chem. Soc.__ 100, 3590–3594) was const

Intramolecular and overall motion of pro
Intramolecular and overall motion of proline: The influence of viscosity on carbon-13 spin-lattice relaxation times
✍ Roxanne Deslauriers; Ian C. P. Smith 📂 Article 📅 1977 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 634 KB

Nuclear magnetic resonance of 13C is used to probe the overall and internal motions of proline. Spin-lattice relaxation times (TI) are reported for proline monomer dissolved in water/glycerol mixtures. Rates of overall molecular motion and internal motion depend on solvent composition but to differe