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Roles of FHIT and WWOX fragile genes in cancer

✍ Scribed by Dimitrios Iliopoulos; Gulnur Guler; Shuang-Yin Han; Teresa Druck; Michelle Ottey; Kelly A. McCorkell; Kay Huebner

Book ID
116333880
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
353 KB
Volume
232
Category
Article
ISSN
0304-3835

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The fragile genes FHIT and WWOX are inac
The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma : Correlations with clinical features
✍ Gulnur Guler; Aysegul Uner; Nilufer Guler; Shuang-Yin Han; Dimitrios Iliopoulos; πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 336 KB

## Abstract ## BACKGROUND __FHIT__ and __WWOX__ are a tumor suppressor and a candidate suppressor that encompass the __FRA3B__ and __FRA16D__ fragile sites at chromosomes 3p14.2 and 16q23.3–24.1, respectively. Reduced or absent Fhit expression has been reported in two‐thirds of invasive breast tum