Role of COX-1- and COX-2-synthesized pro
β
Rosa Ventura MartΓnez; M. Irene DΓaz; G. Patricia HernΓ‘ndez; Adriana M. DomΓngue
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Article
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2000
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John Wiley and Sons
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English
β 142 KB
## Abstract An appropriate animal model for investigation of antiinflammatory analgesic effects of NSAIDs is the painβinduced functional impairment model in the rat (PIFIR model). The PIFIR model provides a model of inflammatory and chronic pain similar to that of clinical gout. We investigated the