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Synthesis and Cyclooxygenase (COX-1/COX-2) Inhibiting Property of 3,4-Diarylfuranones.

✍ Scribed by Manojit Pal; Venugopal Rao Veeramaneni; Srinivas Padakanti; Murali Nagabelli; Akhila Vanguri; Premkumar Mamnoor; Seshagiri Rao Casturi; Parimal Misra; Ramesh Mullangi; Koteswar Rao Yeleswarapu


Publisher
John Wiley and Sons
Year
2003
Weight
13 KB
Volume
34
Category
Article
ISSN
0931-7597

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Inhibition of the cyclooxygenase isoenzy
✍ Peter Teismann; Boris Ferger πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 188 KB πŸ‘ 2 views

To study the possible role of the isoenzymes of cyclooxygenase COX-1 and COX-2 in the MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) mouse model of Parkinson's disease we used acetylsalicylic acid, a COX-1/COX-2 inhibitor, in comparison with meloxicam, a preferential COX-2 inhibitor. As markers