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Role of TLX1 in T-cell acute lymphoblastic leukaemia pathogenesis

✍ Scribed by Irene Riz; Teresa S. Hawley; Helen Johnston; Robert G. Hawley

Book ID
108676163
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
239 KB
Volume
145
Category
Article
ISSN
0007-1048

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## Abstract Most chromosomal translocations observed in T‐cell acute lymphoblastic leukemia (T‐ALL) often produce transcriptional activation of transcription factor oncogenes. Ectopic expression of the __TLX3__ (also known as __HOX11L2__) gene has been shown to be associated with a cryptic t(5;14)(