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Role of thioredoxin-1 in apoptosis induction by α-tocopheryl succinate and TNF-related apoptosis-inducing ligand in mesothelioma cells

✍ Scribed by Ruth E. Freeman; Jiri Neuzil

Book ID
116466609
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
223 KB
Volume
580
Category
Article
ISSN
0014-5793

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## Abstract α‐Tocopheryl succinate (TOS), a vitamin E analog, is a promising anticancer agent due to its abilities to inhibit proliferation and to induce apoptosis in a variety of human malignant cell lines, while being relatively less active toward normal cells. However, the molecular mechanisms u