α-Tocopheryl succinate-induced apoptosis in human gastric cancer cells is modulated by ERK1/2 and c-Jun N-terminal kinase in a biphasic manner

Involvement of c-jun N-terminal kinase a

Involvement of c-jun N-terminal kinase activation in 15-deoxy-δ12,14-prostaglandin J2–and prostaglandin A1–induced apoptosis in AGS gastric epithelial cells

✍ Jean-Dean Liu; Shyr-Yi Lin; Yuan-Soon Ho; Shiann Pan; Ling-Fang Hung; Shu-Huei T 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 224 KB

Cyclopentenone prostaglandins (CyPGs), derivatives of arachidonic acid, have been suggested to exert growth-inhibitory activity through peroxisome proliferator-activated receptor (PPAR)-dependent and -independent mechanisms. Here we examined various eicosanoids for growth inhibition and found that t