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Role of the FGF-2-binding fragment of thrombospondin-1 (TSP-1) in tumor progression

โœ Scribed by A. Resovi; P. Borsotti; S. Bonifacio; P. Oliva; V. Castiglioni; R. Giavazzi; G. Taraboletti

Book ID
117258618
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
66 KB
Volume
129
Category
Article
ISSN
0049-3848

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The role of thrombospondin-1 in tumor progression and angiogenesis
โœ George P. Tuszynski; Roberto F. Nicosia ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 834 KB

Thrombospondin (TSP-1) is a large glycoprotein secreted by platelets and synthesized by many cell types, including endothelial and tumor cells. Although controversy exists about the biological function of TSP-1, the following observations suggest that TSP-1 may potentiate tumor progression. (1) Tumo