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Role of S-adenosylmethionine in DNA synthesis and haemopoiesis

✍ Scribed by Sourial, N.A. ;Amess, J.A.L. ;Amos, R.J.

Book ID
114790287
Publisher
Wiley (Blackwell Publishing)
Year
2009
Weight
331 KB
Volume
34
Category
Article
ISSN
0036-553X

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## Abstract This article describes the radiosynthesis of ^11^C‐labelled S‐adenosylmethionine by an enzymatic process. This methyl donor was prepared by condensation of L‐(methyl‐^11^C) methionine with ATP. The synthesis and purification could be carried out in 20 minutes with a final yield of 80 %.