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The synthesis of S-adenosylmethionine by mutants with defects in S-adenosylmethionine synthetase

✍ Scribed by Hobson, Ann C.

Publisher: Springer
Year: 1976
Tongue: English
Weight: 887 KB
Volume: 144
Category: Article
ISSN: 0026-8925
DOI: 10.1007/bf00277310

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✦ Synopsis

Some metK mutants of Salmonella typhimurium with constitutive methionine biosynthesis have no detectable S-adenosylmethionine (SAM) synthetase, the enzyme which converts methionine to SAM, the postulated corepressor of the methionine pathway. However, these mutants are not auxotrophic for SAM, an essential compound for many reactions.

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