PI3K/Akt inhibition modulates multidrug
PI3K/Akt inhibition modulates multidrug resistance and activates NF-κB in murine lymphoma cell lines
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Mariana G. García; Laura D. Alaniz; Rosalía I. Cordo Russo; Elida Alvarez; Silvi
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Article
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2009
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Elsevier Science
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English
⚖ 825 KB
Upregulation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway has been described in some tumors related to multidrug resistance (MDR). The aim of this work was to analyze the relationship between PI3K/Akt, MDR and NF-kappaB in murine lymphoma cell lines resistant to vincristine (LBR-V160) and