𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Role of neck dissection following concurrent chemoradiation for advanced head and neck carcinoma

✍ Scribed by Véronique-Isabelle Forest; Phuc Félix Nguyen-Tan; Jean-Claude Tabet; Marie-Jo Olivier; Daniel Larochelle; Bernard Fortin; Michel Gélinas; Denis Soulières; Danielle Charpentier; Louis Guertin

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
169 KB
Volume
28
Category
Article
ISSN
1043-3074

No coin nor oath required. For personal study only.

✦ Synopsis

Background. Our primary objective was to determine the role of neck dissection following concomitant chemoradiation (CRT) for advanced stage III-IV head and neck squamous cell carcinoma (HNSCC).

Methods. One hundred eighty-four patients with HNSCC treated with CRT were included. One hundred twenty-three patients reached a regional complete response (CR) after CRT and no neck dissection was performed. Forty-five patients among the 58 who reached a regional partial response (PR) underwent a neck dissection.

Results. Overall, regional CR rate after CRT was 68%. Patients who reached a regional CR (no neck dissection) had an overall neck recurrence rate of 5%. Patients with regional PR who underwent a neck dissection had a 7% neck recurrence rate.

Conclusions. Patients with regional CR not followed by a neck dissection have a low rate of neck recurrence. Systematic neck dissection is not mandatory for patients with nodes less than 6 cm reaching a regional CR. For patients with nodes larger than 6 cm, no firm recommendation can be given because of the small number of patients in this series. If the regional response is incomplete, cervical dissection is warranted. V

📜 SIMILAR VOLUMES

Extent of neck dissection required after
Extent of neck dissection required after concurrent chemoradiation for stage IV head and neck squamous cell carcinoma
✍ Steven B. Cannady; Walter T. Lee; Joseph Scharpf; Robert R. Lorenz; Benjamin G. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 2 views

## Abstract ## Background The management of initially bulky nodal disease after primary nonsurgical treatment for stage IV head and neck squamous cell carcinoma (HNSCC) continues to be a subject of debate. ## Methods A retrospective chart review of neck management in patients after chemoradiatio

Selective neck dissection following adju
Selective neck dissection following adjuvant therapy for advanced head and neck cancer
✍ Vijay Mukhija; Sachin Gupta; Adam S. Jacobson; Jean Anderson Eloy; Eric M. Gende 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 122 KB 👁 1 views

## Abstract ## Background. In the past, surgeons believed that in order to eradicate regional disease, a radical or modified radical neck dissection was necessary. An evolution in surgical principles and the popularization of primary chemoradiation has raised the questions regarding the role of ne

Postoperative complications after chemor
Postoperative complications after chemoradiation for advanced head and neck cancer
✍ Eva Proctor; K. Thomas Robbins; Francisco Vieira; Catherine Hanchett; Grant Somm 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 73 KB 👁 1 views

## Abstract ## Background. To compare the rate of postoperative complications of patients with advanced head and neck cancer treated with the chemoradiation protocol “RADPLAT” with that of a similar cohort of patients treated with primary surgery. ## Methods. We retrospectively analyzed 50 patie

Acceleration of hyperfractionated chemor
Acceleration of hyperfractionated chemoradiation regimen for advanced head and neck cancer
✍ Aaron M. Allen; Mohamed Elshaikh; Francis P. Worden; Carol R. Bradford; Theodoro 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 1 views

## Abstract ## Background. Our aim was to evaluate the acceleration of a hyperfractionated, concurrent chemoradiation regimen (HxCRT) for advanced head and neck squamous cell carcinoma (HNSCC). ## Methods. Patients with unresectable HNSCC were treated based on a previously published HxCRT regime