## Abstract ## Background. In the past, surgeons believed that in order to eradicate regional disease, a radical or modified radical neck dissection was necessary. An evolution in surgical principles and the popularization of primary chemoradiation has raised the questions regarding the role of ne
Planned neck dissection following chemoradiotherapy for advanced head and neck cancer: Is it necessary for all?
✍ Scribed by Phillip K. Pellitteri; Alfio Ferlito; Alessandra Rinaldo; Jatin P. Shah; Randal S. Weber; John Lowry; Jesus E. Medina; Christine G. Gourin; K. Thomas Robbins; Carlos Suárez; Ashok R. Shaha; Eric M. Genden; C. René Leemans; Jean Louis Lefebvre; Luiz P. Kowalski; William I. Wei
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 109 KB
- Volume
- 28
- Category
- Article
- ISSN
- 1043-3074
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✦ Synopsis
In the absence of large-scale randomized trials evaluating dissection versus observation of the involved neck after neoadjuvant chemoradiotherapy, there is a need to collect
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Background. Our primary objective was to determine the role of neck dissection following concomitant chemoradiation (CRT) for advanced stage III-IV head and neck squamous cell carcinoma (HNSCC). Methods. One hundred eighty-four patients with HNSCC treated with CRT were included. One hundred twenty-
## Abstract ## Objectives/Hypothesis: Planned neck dissection following chemoradiation (CR) has been advocated in patients with head and neck squamous cell cancer (HNSCC) with advanced nodal disease and a clinical complete response to CR because of the potential for residual occult nodal disease.
## Abstract ## Background. The role of neck dissection (ND) after definitive chemoradiotherapy for squamous cell head and neck cancer is incompletely defined. We retrospectively reviewed 109 patients with N2–N3 disease treated with chemoradiotherapy to identify predictors of a clinical complete re