## Abstract ## Background. Our aim was to evaluate the acceleration of a hyperfractionated, concurrent chemoradiation regimen (HxCRT) for advanced head and neck squamous cell carcinoma (HNSCC). ## Methods. Patients with unresectable HNSCC were treated based on a previously published HxCRT regime
Postoperative complications after chemoradiation for advanced head and neck cancer
β Scribed by Eva Proctor; K. Thomas Robbins; Francisco Vieira; Catherine Hanchett; Grant Sommes
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 73 KB
- Volume
- 26
- Category
- Article
- ISSN
- 1043-3074
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Background.
To compare the rate of postoperative complications of patients with advanced head and neck cancer treated with the chemoradiation protocol βRADPLATβ with that of a similar cohort of patients treated with primary surgery.
Methods.
We retrospectively analyzed 50 patients treated with RADPLAT and 50 patients treated with primary surgery.
Results.
The rates of complications for local wound problems were 54% and 42%, respectively, for the RADPLAT cohort and the primary surgery cohort. However, the rate of local complications for the subset of RADPLAT patients undergoing cleanβcontaminated surgery was 69% (p = .305). The rates of complications for medical (systemic) problems were 10% and 12%, respectively, for RADPLAT versus primary surgery patients. There was no significant difference in hospitalization time between the groups.
Conclusions.
Among patients with advanced head and neck cancer, surgical complications are high but not significantly different between patients undergoing the chemoradiation protocol βRADPLATβ and those undergoing primary surgery. Β© 2004 Wiley Periodicals, Inc. Head Neck 26: 272β277, 2004
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