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Role of N-methyl-D-aspartate receptors in polychlorinated biphenyl mediated neurotoxicity

โœ Scribed by Leopold Tchapda Ndountse; Hing Man Chan


Book ID
119380756
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
396 KB
Volume
184
Category
Article
ISSN
0378-4274

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โœ Won-Ki Kim; Kwang Ho Ko ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 273 KB

Microglia have been shown to be immunostimulated by inflammatory cytokines and produce a number of toxic mediators. Here we report that immunostimulated microglia can synergistically enhance the Nmethyl-D-aspartate (NMDA) receptor-mediated excitotoxicity in rat cerebellar granule cells (CGC) in cult