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A N-methyl-d-aspartate receptor-mediated neurotoxic effect of aspartate-based hydroxamate compounds in rat primary neuronal cultures

✍ Scribed by Brian Paul Lockhart; Farid Hamedi-Sangsari; Jacques Vignon; Alain Privat; Jorge Vila


Book ID
113126807
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
590 KB
Volume
670
Category
Article
ISSN
0006-8993

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Primary cultures of embryonic rat cerebral cortex were treated after 17 days in vitro for 10 min with a single dose of the non-competitive antagonists of Nmethyl-D-aspartate (NMDA) receptor MK 801, TCP, and GK 11. They were then maintained in vitro for 31, 59, or 73 days, and then processed for the