## Abstract ## Objective The protein deacetylase SirT1 positively regulates cartilage‐specific gene expression, while the proinflammatory cytokine tumor necrosis factor α (TNFα) negatively regulates these same genes. This study was undertaken to test the hypothesis that SirT1 is adversely affected
✦ LIBER ✦
Role of interleukin-1 and tumor necrosis factor α in matrix degradation of human osteoarthritic cartilage
✍ Scribed by Masahiko Kobayashi; Ginette R. Squires; Aisha Mousa; Michael Tanzer; David J. Zukor; John Antoniou; Ulrich Feige; A. Robin Poole
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 151 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0004-3591
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