Role of inositol 1,4,5-triphosphate receptors in neurite outgrowth of chick DRG neurons
β Scribed by Kohtaro Takei; Ryong-Moon Shin; Katsuhiko Mikoshiba
- Book ID
- 117364961
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 115 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0168-0102
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Inositol 1,4,5-trisphosphate receptors (IP 3 R) are mediators of second messenger-induced intracellular calcium release. Three isoforms are known to be expressed in brain, but their regional distributions and cellular localizations are little known. In order to better understand the roles of IP 3 re
## Abstract The morphogenetic role of the neurotransmitter acetylcholine was studied in cultures of dorsal root ganglia (DRG) neurons obtained from E12 and E18 chick embryos. With this model we have evaluated neurofilament expression and neurite outgrowth following cholinergic agonist and antagonis
The inositol 1,4,5-triphosphate receptor (IP 3 R) regulates the release of calcium from intracellular stores. In the present study, the distribution of IP 3 R in the rat main olfactory bulb was determined by immunohistochemistry. Immunofluorescence was used to double label for IP 3 R and for β₯-amino