Inositol 1,4,5-trisphosphate receptors (IP 3 R) are mediators of second messenger-induced intracellular calcium release. Three isoforms are known to be expressed in brain, but their regional distributions and cellular localizations are little known. In order to better understand the roles of IP 3 re
Presence of the inositol 1,4,5-triphosphate receptor isoforms in the nucleoplasm
β Scribed by Yang Hoon Huh; Seung Hyun Yoo
- Book ID
- 117106023
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 890 KB
- Volume
- 555
- Category
- Article
- ISSN
- 0014-5793
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Ca 2Ψ signals mediate the hepatic effects of numerous hormones and growth factors. Hepatic Ca 2Ψ signals are elicited by the inositol trisphosphate receptor, an intracellular Ca 2Ψ channel. Three isoforms of this receptor have been identified; they are expressed and regulated differently. We investi
The inositol 1,4,5-triphosphate receptor (IP 3 R) regulates the release of calcium from intracellular stores. In the present study, the distribution of IP 3 R in the rat main olfactory bulb was determined by immunohistochemistry. Immunofluorescence was used to double label for IP 3 R and for β₯-amino